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REVIEW ARTICLE
Year : 2018  |  Volume : 1  |  Issue : 2  |  Page : 61-70

Breast cancer and Fertility Part 2- Pregnancy Associated Breast Cancer


Department of Reproductive Medicine, Mother and Child Hospital, New Delhi, India

Correspondence Address:
Nalini Mahajan
Mother and Child Hospital, D-59 Defence Colony, New Delhi - 110 024
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/tofj.tofj_8_18

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Pregnancy-associated breast cancer (PABC) refers to breast cancer (BC) diagnosed during pregnancy or within the first postpartum year. The increasing incidence follows the increase in age at first childbirth. Diagnostic delay due to physiological breast changes of pregnancy leads to the tumor being diagnosed at a more advanced stage. Since the termination of pregnancy does not alter the course of disease, patients can be offered BC management during pregnancy with a good outcome. Chemotherapy (CT) can be given safely during the second and third trimester of pregnancy. In the first trimester, the option of surgery is available while during puerperium, radiotherapy can be safely administered in addition to CT. Prognosis is related to the stage and grade of the tumor. Neonatal outcomes are reassuring. This article gives an overview of the diagnosis, management, and prognosis of PABC.


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