| CASE REPORT |
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| Year : 2020 | Volume
: 3
| Issue : 1 | Page : 42-45 |
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Live birth following the transfer of a euploid blastocyst derived from monopronuclear zygote
Surleen Kaur1, Kirtirupa Nandi1, Shipra Gupta1, Nidhi Sehrawat2
1 Reproductive Medicine Unit, Ferticity Fertility Clinics, Delhi, India
2 Department of Reproductive Medicine, Mother and Child Hospital, Delhi, India
Correspondence Address:
Dr. Surleen Kaur
Ferticity Fertility Clinics, 12, Navjeevan Vihar, Malviya Nagar, Delhi - 110 017
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/tofj.tofj_1_20
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The objective of the present study is to report a case of a live birth following the transfer of a blastocyst derived from monopronuclear zygote that was found to be an euploid by preimplantation genetic testing for aneuploidy (PGT-A). The study was conducted at a tertiary care-assisted reproductive technology center. A 35-year-old female with a secondary infertility, polycystic ovaries, and with the history of recurrent implantation failure underwent an in vitro fertilization cycle followed by a frozen embryo transfer cycle. The main outcome measure was clinical pregnancy and live birth. The patient was considered pregnant after obtaining a βhCG level of 1334 mIU/mL after 14 days following embryo transfer and delivered a healthy baby girl at 30 weeks by cesarean section. In this study, transfer of frozen-thawed monopronuclear-derived blastocyst that was detected euploid with PGT-A, resulted in a healthy live birth. Therefore, we suggest that embryos from monopronuclear zygotes should not be discarded but instead be screened by PGT-A to ascertain the euploid status, especially in the absence of bipronuclear-derived embryos.
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